[瓜咕噜]

copy下面代码到你的OpeningFcn函数里面就可以了

set(hObject,'Units','pixels');
figuresize=get(hObject,'Position');
screensize=get(0,'screensize');
set(gcf,'outerposition',[(screensize(3)-figuresize(3))/2,(screensize(4)-figuresize(4))/2,figuresize(3),figuresize(4)]);